Mediators of Inflammation

C-Reactive Protein and Arteriosclerosis


Status
Published

1Cardiovascular Center Oberallgäu-Kempten, Kempten, Germany

2Molecular Pathology, University of Yamanashi, Japan

3German Heart Center, Munich, Germany

4University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, Birmingham, USA

5Laboratory Medicine, Robert Bosch Hospital, Stuttgart, Germany


C-Reactive Protein and Arteriosclerosis

Description

Over the last two decades, the role of C-reactive protein (CRP), the prototype human acute phase protein, in cardiovascular disease has been extensively studied and discussed. The underlying reasons are briefly summarized as follows. First, arteriosclerosis is an inflammatory disease and CRP is a mediator of inflammation. Second, CRP has been identified as a cardiovascular risk marker. Third, CRP may be causally involved in atherogenesis and its sequelae. Lastly, CRP may be a target for cardiovascular drug development.

Controversial data have been accumulated that either support or contradict these scientific concepts. We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the role of C-reactive protein in cardiovascular disease. Potential topics include, but are not limited to:

  • C-reactive protein: biological function and role in acute phase response
  • C-reactive protein as a cardiovascular risk marker
  • C -reactive protein in the arterial wall
  • Animal models of C-reactive protein and cardiovascular disease
  • Inhibiting C-reactive protein for the treatment of cardiovascular disease

Before submission authors should carefully read the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/cpa/ according to the following schedule:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 646817
  • - Editorial

C-Reactive Protein and Arteriosclerosis

Jan Torzewski | Jianglin Fan | ... | Michael Torzewski
  • Special Issue
  • - Volume 2014
  • - Article ID 319215
  • - Review Article

Recognition Functions of Pentameric C-Reactive Protein in Cardiovascular Disease

Alok Agrawal | Toh B. Gang | Antonio E. Rusiñol
  • Special Issue
  • - Volume 2014
  • - Article ID 979132
  • - Research Article

Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits

Qi Yu | Zhengcao Liu | ... | Jianglin Fan
  • Special Issue
  • - Volume 2014
  • - Article ID 683598
  • - Review Article

Animal Models of C-Reactive Protein

Michael Torzewski | Ahmed Bilal Waqar | Jianglin Fan
  • Special Issue
  • - Volume 2014
  • - Article ID 929536
  • - Research Article

Change in Growth Differentiation Factor 15, but Not C-Reactive Protein, Independently Predicts Major Cardiac Events in Patients with Non-ST Elevation Acute Coronary Syndrome

Alberto Dominguez-Rodriguez | Pedro Abreu-Gonzalez | ... | Francisco Bosa-Ojeda
  • Special Issue
  • - Volume 2014
  • - Article ID 757123
  • - Review Article

C-Reactive Protein and Coronary Heart Disease: All Said—Is Not It?

Frederik Strang | Heribert Schunkert
  • Special Issue
  • - Volume 2014
  • - Article ID 353614
  • - Research Article

Inhibiting C-Reactive Protein for the Treatment of Cardiovascular Disease: Promising Evidence from Rodent Models

Alexander J. Szalai | Mark A. McCrory | ... | Rosanne M. Crooke
  • Special Issue
  • - Volume 2014
  • - Article ID 561428
  • - Review Article

C-Reactive Protein in Human Atherogenesis: Facts and Fiction

Oliver Zimmermann | Kefei Li | ... | Jan Torzewski
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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