Review Article

Neuroendoscopic Resection of Intraventricular Tumors: A Systematic Outcomes Analysis

Table 1

demonstrating articles included in the study by publication year with corresponding data regarding tumor histology, number of patients (n), presence of preoperative hydrocephalus, use of navigation/stereotactic tools, adjunctive endoscopic procedures, time spent in the operating room (OR time), hospital stay, procedure-related complications, resection success, and recurrence rate for 668 intraventricular tumors in 40 studies that underwent attempted endoscopic resection.

AuthorYear Tumor histology
Preoperative Hydrocephalus
Navigation/
stereotaxy
Adjunctive procedures
Mean OR time
(min)
Mean hospital stay
(days)
Complications
Complete or near-complete resection
(%)
Recurrence

Lewis et al. [11]19947Colloid cyst (7)50No1271.717 (100)1
Abdullah and Caemaert [21]19953Craniopharyngioma (3)NDNDNDNDND01 (33.4)2
Abdou and Cohen [3]199813Colloid cyst (13)130NoNDND010 (76.9)0
Gaab and Schroeder [12]199819Colloid cyst (7), Subependymoma (3), low-grade astrocytoma (2), germinoma (1), pineal cyst (1), epidermoid cyst (1), hemangioma (1), cavernoma (1), CPP (1), ependymoma (1) 11Navigation (4)ETV (2), septostomy (1), stent (2)85ND313 (68.4)1
King et al. [51]199913Colloid cyst (13)120Septostomy (13)942.3210 (83.3)0
Rodziewicz et al. [36]200012Colloid cyst (12)60Septostomy (12)NDND111 (91.7)1
Decq et al. [55]200022Colloid cyst (22)210NoNDND014 (63.6)1
Kehler et al. [8]200110Colloid cyst (10)NDNDNDNDND39 (90)1
MacArthur et al. [56]20027Colloid cyst (3), low-grade astrocytoma (1), ependymoma (1), unknown (2)NDNDNDNDNDND4 (57.1)0
Jho and Alfieri [57]20022Colloid cyst (2)ND0NoNDND02 (100)0
Sgaramela et al. [58]20031Colloid cyst (1)NDNDNDNDND01 (100)0
Hellwig et al. [34]200320Colloid cyst (20)19Stereotaxy (9), Navigation (11)Intraoperative ventriculography (11)250 (stereotactic), 150 (navigated)7418 (90)1
Husain et al. [20]200325Colloid cyst (11), ependymal cyst (2), choroid plexus cyst (2), septum Pellucidum cyst (2), arachnoid cyst (2), neurocysticercosis (2), craniopharyngioma (2), pineoblastoma (1), pineal Cyst (1)ND0NoND3220 (80)ND
Souweidane [33, 37]20052Colloid cyst (1), glioneuronal tumor (1)10NoNDND02 (100)0
Jeon et al. [59]20051Choroid plexus cyst (1)10NoND3711 (100)ND
Longatti et al. [43]200661Colloid cysts (61)530No876.7438 (62.3)7
Souweidane and Luther [32]20067Ependymoma (2), central neurocytoma (2), low-grade glioneuronal tumor (2), subependymoma (1) 70No1172.625 (71.4)0
Harter et al. [60]20061Dysembryoplastic neuroepithelial tumor (1)1NDNDNDNDND1 (100)ND
Lekovic et al. [46]20062Hypothalamic hamartomas (2)NDNavigation (2)NoNDND01 (50)ND
Grondin et al. [2]200725Colloid cysts (25)220No1043.8324 (96)1
Horn et al. [48]200728Colloid cysts (28)17Navigation (28)No1745.4310 (52.6), ND 90
Levine et al. [61]200735Colloid cysts (35)NDNDNDNDND732 (91.4)7
Greenlee et al. [31]200835Colloid cysts (35)NDFrameless stereotaxy (35)No933329 (82.8)1
El-Ghandour [30]200910Colloid cysts (10)100ETV (2)NDND18 (80)0
Stark et al. [38]20091Papillary ependymoma (1)1Navigation (1)NoNDND11 (100)0
Romano et al. [50]20091Central neurocytoma (1)10ETV (1)NDND01 (100)0
Oertel et al. [19]200911Unidentified (11)ND0ETV (11)71ND94 (36.3)ND
Mishra et al. [39]201059Colloid cyst (59)59Navigation (59)NoNDND1953 (89.8)0
Najjar et al. [49]20107Colloid cyst (3), craniopharyngioma (1), low-grade astrocytoma (1), pineal cyst (1), unknown (1)6Navigation (2)ETV (1), Septostomy (2)NDND04 (57.1)1
Boogaarts et al. [29]201190Colloid cyst (90)NDStereotaxy (18)ETV (7)79ND3246 (57.5), ND 1024
Ahmad and Sandberg [16]20101CPP (1)10ETV (1)NDND01 (100)0
Naftel et al. [28]20114Colloid cyst (2), hypothalamic hamartoma (2)1Navigation (2)NoNDND03 (75)ND
Dlouhy et al. [45]20114Colloid cyst (3), pineoblastoma (1)NDNDNDNDNDND4 (100)ND
Delitala et al. [27]20117Colloid cyst (7)4Navigation (4)NoNDND06 (85.7)0
Sood et al. [41]20112Pineal cyst (1), Pineoblastoma (1)20NoNDNDND2 (100)ND
Wilson et al. [26]201222Colloid cyst (22)19Navigation (19)No180ND021 (95.4)0
Margetis and Souweidane [25]201267Colloid cyst (67)NDNavigation (67)NoNDND466 (98.5)3
Mohanty et al. [44]20123Craniopharyngioma (2), subependymoma (1)20VP-shunt placement (2)NDND22 (66.7)0
Selvanathan et al. [42] 20131Ependymoma (1)1NavigationETVNDND11 (100)1
Drees et al. [62]201226Hypothalamic hamartoma (26)NDNDNDNDND140 (0)ND

Total: 40
studies
Total: 668
patients
ā€‰Total: 296/352 patients (84.1%)Total: 262/581 patients (45.1%)Total: 70/581 patients (12.0%)Mean: 107.5 minutesMean: 4.8 daysTotal: 123/592 patients (20.8%)Total: 487/649 patients (75.0%)Total: 53/533 patients (9.9%)

CPP: choroid plexus papilloma, ND: no data, ETV: endoscopic third ventriculostomy, VP-shunt: ventriculoperitoneal shunt, and min: minutes.