Research Article
Surgery for Perforated Peptic Ulcer: Is Laparoscopy a New Paradigm?
Table 2
Surgical approaches, sepsis group (n = 52).
| Variable | Laparoscopy n = 6 (11.5%) | Laparotomy n = 46 (88.5%) | Total n = 52 (100%) | value |
| Sex | | | | 0.243 | Male | 5 (83.3%) | 27 (58.7%) | 32 (61.5%) | | Female | 1 (16.7%) | 19 (41.3%) | 20 (38.5%) | | Age (years, median, and range) | 48 (41–78) | 68 (39–94) | 62.5 (39–94) | 0.078 | Comorbidities | 5 (83.3%) | 39 (84.8%) | 44 (84.6%) | 0.926 |
| Boey score | | | | 0.132 | 0 | 1 (16.9%) | 1 (2.2%) | 2 (3.8%) | | 1 | 0 (0%) | 16 (34.8%) | 16 (30.8%) | | 2 | 2 (33.3%) | 15 (32.6%) | 17 (32.7%) | | 3 | 3 (50%) | 14 (30.4%) | 17 (32.7%) | |
| Categorical Boey score | | | | 0.651 | Boey score <2 | 1 (16.7%) | 17 (37%) | 18 (34.6%) | | Boey score ≥ 2 | 5 (83.3%) | 29 (63%) | 34 (65.4%) | |
| Symptoms-surgery delay (hours) | | | | 0.382 | <12 | 2 (33.3%) | 7 (15.2%) | 9 (17.3%) | | 12 < 24 | 0 (0%) | 7 (15.2%) | 7 (13.5%) | | >24 | 4 (66.7%) | 32 (69.6%) | 36 (69.2%) | |
| Procedure | | | | 0.519 | Suture (nonresection procedure) | 6 (100%) | 43 (93.5%) | 49 (94.2%) | | Resection procedure | 0 (0%) | 3 (6.5%) | 3 (5.8%) | |
| Biopsy (only gastric location) | | | | 0.848 | Yes | 1 (100%) | 21 (75%) | 22 (75.9%) | | No | 0 (0%) | 5 (17.9%) | 5 (17.2%) | | Not applied | 0 (0%) | 2 (7.1%) | 2 (6.9%) | | Operative time (minutes, median, and range) | 122.5 (60–165) | 100 (42–245) | 100 (42–245) | 0.483 | Early complications (<30 days) | 2 (33.3%) | 35 (76.1%) | 37 (71.2%) | 0.047 |
| Complications (Clavien-Dindo) | | | | 0.262 | Grade I | 0 (0%) | 0 (0%) | 0 (0%) | | Grade II | 0 (0%) | 6 (17.1%) | 6 (16.2%) | | Grade III | 1 (50%) | 3 (8.6%) | 4 (10.8%) | | Grade IV | 0 (0%) | 11 (31.4%) | 11 (29.7%) | | Grade V | 1 (50%) | 15 (42.9%) | 16 (43.2%) | | Mortality | 1 (16.7%) | 15 (32.6%) | 16 (30.8%) | 0.653 | Late complications (>30 days) | 1 (20%) | 9 (32.1%) | 10 (30.3%) | 0.586 | Hospital stay (days, median, and range) | 7.5 (5–79) | 13.5 (1–152) | 13 (1–152) | 0.354 | Oral intake (days, median, and range) | 3 (1–5) | 4 (2–42) | 4 (1–42) | 0.029 |
|
|