Research Article

Surgery for Perforated Peptic Ulcer: Is Laparoscopy a New Paradigm?

Table 2

Surgical approaches, sepsis group (n = 52).

VariableLaparoscopy n = 6 (11.5%)Laparotomy n = 46 (88.5%)Total n = 52 (100%) value

Sex0.243
Male5 (83.3%)27 (58.7%)32 (61.5%)
Female1 (16.7%)19 (41.3%)20 (38.5%)
Age (years, median, and range)48 (41–78)68 (39–94)62.5 (39–94)0.078
Comorbidities5 (83.3%)39 (84.8%)44 (84.6%)0.926

Boey score0.132
 01 (16.9%)1 (2.2%)2 (3.8%)
 10 (0%)16 (34.8%)16 (30.8%)
 22 (33.3%)15 (32.6%)17 (32.7%)
 33 (50%)14 (30.4%)17 (32.7%)

Categorical Boey score0.651
 Boey score <21 (16.7%)17 (37%)18 (34.6%)
 Boey score ≥ 25 (83.3%)29 (63%)34 (65.4%)

Symptoms-surgery delay (hours)0.382
 <122 (33.3%)7 (15.2%)9 (17.3%)
 12 < 240 (0%)7 (15.2%)7 (13.5%)
 >244 (66.7%)32 (69.6%)36 (69.2%)

Procedure0.519
 Suture (nonresection procedure)6 (100%)43 (93.5%)49 (94.2%)
 Resection procedure0 (0%)3 (6.5%)3 (5.8%)

Biopsy (only gastric location)0.848
 Yes1 (100%)21 (75%)22 (75.9%)
 No0 (0%)5 (17.9%)5 (17.2%)
 Not applied0 (0%)2 (7.1%)2 (6.9%)
Operative time (minutes, median, and range)122.5 (60–165)100 (42–245)100 (42–245)0.483
Early complications (<30 days)2 (33.3%)35 (76.1%)37 (71.2%)0.047

Complications (Clavien-Dindo)0.262
 Grade I0 (0%)0 (0%)0 (0%)
 Grade II0 (0%)6 (17.1%)6 (16.2%)
 Grade III1 (50%)3 (8.6%)4 (10.8%)
 Grade IV0 (0%)11 (31.4%)11 (29.7%)
 Grade V1 (50%)15 (42.9%)16 (43.2%)
Mortality1 (16.7%)15 (32.6%)16 (30.8%)0.653
Late complications (>30 days)1 (20%)9 (32.1%)10 (30.3%)0.586
Hospital stay (days, median, and range)7.5 (5–79)13.5 (1–152)13 (1–152)0.354
Oral intake (days, median, and range)3 (1–5)4 (2–42)4 (1–42)0.029