Optimal Tolerance Design and Optimization for a Pharmaceutical Quality Characteristic

Table 8

Optimal solutions from the RD stage.

Control factors (𝑥)			Hardness (𝑦)		Terahertz refractive index (𝑡)		𝜌^∗𝑦𝑡
𝑥^∗1	𝑥^∗2	𝑥^∗3	𝜇^∗𝑦	𝜎𝑦^2∗	𝜇^∗𝑡	𝜎𝑡^2∗
−0.2999	−0.6219	−1.6810	5.0000	0.3792	1.3061	0.0070	0.8684