Data Mining Analysis of Gene Prognostic Markers of Metastatic Skin Cancer Based on the Elastic Network Method

Table 2

Gene prognostic markers closely related to the recurrence of metastatic skin cancer.

Gene ID	Index.min	HR (95%CI)	value	Gene Title
Protective gene
SSH3	−0.02359	0.97669	0.04283	Slingshot protein phosphatase 3
KRT6B	−0.01986	0.98034	0.02243	Keratin 6B
CLIC5	−0.01436	0.98575	0.02136	Chloride intracellular channel 5
ACER1	−0.00988	0.99016	0.04928	Alkaline ceramidase 1 purinergic receptor P2Y
P2RY14	−0.00935	0.99069	0.00160	G-protein coupled, 14 polycystic kidney and hepatic
PKHD1L1	−0.00810	0.99193	0.00853	Disease 1 (autosomal recessive)-like 1
C1orf200	−0.00768	0.99235	0.00448	Chromosome 1 open reading frame 200 leukocyte immunoglobulin-like
LILRA1	−0.00709	0.99294	0.00310	Receptor, subfamily A (with TM domain), member 1
GLTP	−0.00701	0.99301	0.04771	Glycolipid transfer protein
DOCK11	−0.00689	0.99313	0.02809	Dedicator of cytokinesis 11
KRT6C	−0.00595	0.99407	0.02675	Keratin 6C
FGL2	−0.00358	0.99642	0.01206	Fibrinogen-like 2
CP	−0.00036	0.99964	0.03032	Ceruloplasmin (ferroxidase)
Risk gene
FERMT1	0.00012	1.00012	0.02223	Fermitin family member 1
KRT80	0.00571	1.00573	0.01887	Keratin 80 serpin peptidase inhibitor
SERPINB7	0.00727	1.00730	0.01995	Clade B (ovalbumin), member 7
PPL	0.00902	1.00906	0.00467	Periplakin
RHOV	0.01237	1.01245	0.02123	Ras homolog family member V
PIGW	0.01680	1.01694	0.00312	Phosphatidylinositol glycan anchor biosynthesis, class W
TRIM16	0.01726	1.01741	0.01677	Tripartite motif containing 16-like
RNF39	0.02208	1.02233	0.03653	Ring finger protein 39
MUM1	0.02210	1.02234	0.01205	Melanoma-associated antigen (mutated) 1
S100A2	0.02290	1.02316	0.00902	S100 calcium binding protein A2
NMU	0.02936	1.02980	0.00427	Neuromedin U
VSIG10 L	0.03603	1.03668	0.03076	V-set and immunoglobulin
SCN4A	0.04152	1.04239	0.00319	Domain containing 10-like sodium channel, voltage-gated, type IV, alpha subunit