Today’s world is drifting in all new-fangled technology revolution due to the influence of cloud computing and Internet of Things (IoT) technologies. We experience altogether a different capability when these two technologies become a hybrid. There are a plenty of new tools and applications coming up in a day-to-day manner in these two fields for our life. However, there are many complex real-life problems in these fields, which require us to solve them by using mathematical methods and efficient algorithms. We shall think about these new challenges from the points of both mathematics and computers.

The main focus of this special issue is on the new ideas, cutting-edge information, new technologies, and applications in the fields of cloud computing and IoT, with a special emphasis on how to solve various problems by using applied mathematics and algorithms. Potential topics include, but are not limited to:

• Resource scheduling in cloud computing
• Mathematical and discrete modeling in IoT
• Security models and encryption algorithms in cloud computing and IoT
• Network topology in cloud computing
• Complex networks in IoT
• Cooperative data processing for IoT
• Virtualization in cloud computing
• Bioinspired and Evolutionary algorithms for IoT
• IoT networking and communication
• Other related topics

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/mpe/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mpe/ama/ according to the following timetable: