Serial Assessment of Cardiac Function during and following Mitoxantrone Infusion in 30 Consecutive Patients with Multiple Sclerosis

Table 1

Mean values for heart rate, left ventricular enddiastolic dimension (LVEDD), ejection fraction (EF), and fractional shortening (FS). Standard deviation and number of patients in parenthesis. ^∗𝑃value≤.05.

	Treatment start	At cessation of treatment	At the beginning of follow-up	At the end
Heart rate (rpm)	77 (12, 28)	76 (16, 30)	76 (14, 19)	73 (13, 19)
LVEDD (mm)	46 (5, 25)	44 (5, 27)	45 (5, 19)	46 (5, 19)
EF (%)	71 (9, 24)	65 (9, 27)*	63 (6, 19)	62 (7, 19)
FS (%)	41 (8, 24)	36 (6, 26)*	33 (5, 19)	33 (5, 19)