Research Article

Validation of the Danish Version of Functional Assessment of Multiple Sclerosis: A Quality of Life Instrument

Table 3

Construct validity of FAMS subscale scores and total score.

Characteristics of the respondentsMobilitySymptomsEmotional well-beingGeneral contentmentThinking/
fatique
Family/social well-beingFAMS total

Centre:
(i) Haslev ( )13.3 (5.2)21.7 (4.8)*20.0 (6.2)17.9 (5.8)20.9 (7.9)*21.4 (5.2)*114.8 (26.3)*
(ii) Ry ( )11.7 (5.0)19.9 (5.6)*18.6 (6.7)17.6 (6.2)17.9 (8.9)*19.7 (6.1)*105.3 (29.4)*

Gender:
(i) Men ( )11.9 (4.5)21.3 (4.8)19.8 (5.6)17.8 (5.5)19.0 (8.7)21.4 (4.9)111.2 (26.3)
(ii) Women ( )13.1 (5.6)20.7 (5.5)19.1 (6.9)17.7 (6.2)20.0 (8.3)20.1 (6.0)110.4 (29.2)

Age group:
(i) Under 40 years ( )14.9 (4.7)*22.8 (3.6)21.5 (5.3)19.5 (4.7)21.1 (8.0)19.5 (6.7)120.0 (24.7)
(ii) 40–49 years ( )13.4 (5.9)*20.4 (5.6)18.9 (7.0)17.3 (6.7)18.5 (8.3)19.6 (6.1)108.0 (30.0)
(iii) 50–59 years ( )11.5 (4.9)*30.4 (4.7)18.7 (6.7)16.9 (5.7)19.0 (8.6)50.7 (5.1)107.1 (27.2)
(iv) Over 60 years ( )12.3 (4.6)* 21.5 (5.6) 20.0 (5.8) 18.5 (5.6) 20.5 (8.6) 22.0 (5.1)113.9 (27.3)

Disease duration:
(i) 2 years or less ( )12.5 (4.9)20.3 (5.6)18.8 (6.8)16.5 (5.1)18.0 (10.1)*21.2 (5.1)107.2 (30.0)
(ii) 3–5 years ( )13.5 (5.7)21.1 (4.6)19.1 (5.4)16.6 (5.1)18.3 (6.7)*18.9 (5.2)107.4 (24.4)
(iii) 6–9 years ( )13.1 (5.5)21.3 (5.7)20.4 (6.1)19.0 (5.6)22.9 (7.6)*20.4 (6.1)116.0 (27.1)
(iv) 10–19 years ( )12.4 (5.2)20.3 (5.3)19.5 (6.4)17.6 (6.4)18.0 (9.2)*20.6 (5.7)108.2 (28.9)
(v) 20 years or more ( )12.3 (4.6)22.2 (4.3)18.9 (7.6)18.5 (6.4)20.4 (7.8)*22.3 (5.5)114.5 (29.5)

Type of MS:
(i) Relapsing remitting ( )14.9 (5.6)*21.2 (5.4)20.7 (6.5)18.3 (5.8)20.2 (9.6)19.6 (6.1)114.7 (30.4)
(ii) Secondary progressive ( )11.5 (4.8)*20.6 (5.0)18.8 (6.5)17.4 (6.4)19.1 (8.1)21.3 (5.5)108.5 (27.4)
(iii) Primary progressive ( )12.4 (3.9)*21.8 (5.1)19.2 (6.2)18.1 (5.0)20.3 (7.8)20.7 (5.2)111.4 (25.9)

Ambulation status:
(i) Walking independently (EDSS < 5.5) ( )15.1 (5.2)*20.7 (5.1)20.0 (5.9)18.2 (5.4)19.3 (8.7)19.6 (5.4)112.8 (25.9)
(ii) Walking with aid (EDSS 6.0–6.5) ( )11.8 (4.5)*21.0 (5.3)19.5 (6.4)17.9 (5.8)20.0 (8.4)21.9 (5.3)111.6 (28.4)
(iii) Wheelchair user (EDSS > 7.0) ( )8.6 (4.1)*21.2 (5.4)17.3 (8.1)15.9 (8.0)19.0 (8.4)18.7 (6.8)100.6 (32.5)

*Indicates statistically significant difference ( ).