Validation of the Danish Version of Functional Assessment of Multiple Sclerosis: A Quality of Life Instrument

Table 4

Responsiveness to change: mean (sd) FAMS scores at admission and discharge for individuals who had same, better, or worse score at discharge on question 51: “Satisfaction with the way I handle my illness.’’

Satisfaction with the way; I handle my illness (Q51)	Mobility	Symptoms	Emotional well-being	General contentment	Thinking/; fatique	Family/social well-being	FAMS total
Same score (𝑛=111):
(i) Score at admission	13.1 (5.7)	21.3 (4.9)	20.6 (5.9)	18.6 (5.8)	21.2 (7.8)	22.0 (5.0)	116.4 (27.0)
(ii) Change at discharge	0.8 (4.2)	0.9 (3.4)*	0.7 (4.1)	1.1 (4.1)*	1.6 (5.0)*	−0.3 (3.1)	4.8 (16.9)*
(iii) Effect size	0.15	0.19	0.12	0.18	0.20	−0.05	0.18
Better score (𝑛=43):
(i) Score at admission	12.7 (5.0)	21.0 (5.2)	18.4 (6.0)	16.8 (5.6)	18.5 (8.3)	19.0 (6.0)	106.3 (24.7)
(ii) Change at discharge	2.3 (4.0)*	1.5 (4.0)*	2.9 (4.5)*	2.5 (3.9)*	3.3 (7.5)*	1.5 (3.8)*	14.0 (16.8)*
(iii) Effect size	0.44	0.29	0.48	0.45	0.40	0.24	0.57
Mean dif. from “same score” group
(i) Mean (95% CI)	1.5 (0.1; 3.0)*	0.6 (−0.7; 1.8)	2.2 (0.7; 3.7)*	1.5 (0.0; 2.9)*	1.7 (−0.4; 3.7)	1.7 (0.6; 2.9)*	9.2 (3.0; 15.2)*
Worse score (𝑛=26):
(i) Score at admission	11.5 (5.0)	19.7 (5.4)	17.4 (7.0)	16.0 (5.9)	16.7 (9.6)	17.6 (5.8)	97.8 (29.8)
(ii) Change at discharge	−0.4 (5.6)	−0.2 (2.9)	−0.9 (5.1)	−0.7 (4.0)	−1.2 (6.8)	−1.2 (2.7)*	−7.3 (23.1)
(iii) Effect size	−0.09	−0.03	−0.13	−0.12	−0.12	−0.21	−0.25
Mean dif. from“same score”group
(i) Mean (95% CI)	−1.2 (−3.2; 0.7)	1.1 (−2.5; 0.3)	−1.6 (−3.5; 0.3)	−1.8 (−3.5; 0)*	−2.8 (−5.1;−.04)*	−1.0 (−2.3; 0.4)	−12.1 (−20.0;−4.3)*

*Indicates statistically significant difference (𝑃<0.05).