Multiple Sclerosis International / 2011 / Article / Tab 2

Research Article

Serum Metabolic Profile in Multiple Sclerosis Patients

Table 2

Concentration of circulating creatinine, pyrimidine (β-pseudouridine and uridine), oxypurines (hypoxanthine, xanthine and uric acid) malondialdehyde (MDA), nitrite and nitrate (NO2 + NO3), and ascorbic acid determined by HPLC in serum samples of healthy controls and MS patients.

Controls ( )MS patients ( )

Creatinine56.87 ± 17.9871.10 ± 19.27a
Uracile1.97 ± 0.902.11 ± 1.04
β-pseudouridine3.03 ± 1.244.67 ± 1.71a
Uridine4.83 ± 2.197.20 ± 1.82a
Hypoxanthine4.19 ± 1.5812.30 ± 4.84a
Xanthine1.44 ± 0.964.03 ± 2.20a
Uric acid258.08 ± 50.39299.88 ± 70.17a
MDA0.005 ± 0.0040.84 ± 0.54a
NO2 + NO369.06 ± 29.04107.94 ± 43.87a
Ascorbic acid57.52 ± 14.8137.36 ± 10.95a

Values are means ± standard deviations and are expressed in μmol/L serum.
asignificantly different from controls ( ).