Research Article

Exploring the Association between Retinal Nerve Fiber Layer Thickness and Initial Magnetic Resonance Imaging Findings in Patients with Acute Optic Neuritis

Table 1

Demographic and clinical characteristics among optic neuritis patients.

Demographics/characteristics

Number of patients50
Mean age in years (range)34 (18–50)
Male: female10 : 40
CIS*: CDMS29 :  21
Pain (%)42/50 (84)
Mono-focal§: Multi-focal (%)18 : 32
Abnormal MRI# (%)32/50 (64)
Abnormal CSF** (%)14/20 (70)
Corticosteroids (%)25/50 (50)

Ratio of male to female patients included in the study; ratio of * clinically isolated syndrome patients to clinically definite MS patients; number of patients presenting with § mono-focal versus multi-focal optic neuritis as a CIS at baseline; 10# number and percentage of abnormal magnetic resonance imaging scans at presentation; 9** number and percentage of patients with positive oligoclonal bands in their cerebrospinal fluid analysis at baseline:     number and percentage of patients who received treatment with the equivalent of 1000 mg intravenous methylprednisolone for three days for acute optic neuritis.