Optical Coherence Tomography in Multiple Sclerosis and Neuromyelitis Optica: An Update

Table 2

Comparison of RNFL thickness (μm) between both eyes of patients diagnosed of multiple sclerosis who have suffered unilateral optic neuritis and healthy control subjects.

	MS with ON	MS without ON	Control
Siepman et al. [13]	72.2 (14.4)	89.5 (14.2)	—
Khanifar et al.* [14]	83.0 (14.0)	90.5 (13.2)	97
Costello et al. [23]	79.5 (18.8)	97.0 (14.3)	—
Bock et al. [27]	86.2 (16.2)	97.0 (13.1)	105.2 (9.4)
Quelly et al. [30]	78.01 (17.43)	95.24 (11.64)	—
Merle et al. [31]	80.81 (18.4)	96.7 (15.8)	106 (12.2)
Oreja-Guevara et al. [32]	76.42 (16.87)	89.45 (17.68)	—
Frohman et al. [33]	70.3 (13.4)	101.8 (6)	101.9 (8.9)
Burkholder et al. [21]	85.7 (19.0)	95.6 (14.5)	104.5 (10.7)
Spain et al. [34]	75.81	90.93	—
Siger et al. [22]	83.92 (17.63)	94.38 (15.0)	100.3 (12.1)
Pueyo et al. [35]	84.46	94.20	104.97
Zaveri et al. [36]	81.8 (19.3)	95.6 (15.0)	104.6 (10.3)
Pulicken et al. [37]	84.2 (14.7)	95.9 (14)	102.7 (11.5)
Gundogan et al. [20]	—	107.6 (16.3)	110.9 (10.3)
Cheng et al. [38]	76.12 (14.92)	96.45 (11.73)	—
Fisher et al. [10]	85 (17)	96 (14)	105 (12)

*Heidelberg Spectralis. Value for normals taken from normative database.
MS: multiple sclerosis.
ON: optic neuritis.