Clinical Study

Overall Memory Impairment Identification with Mathematical Modeling of the CVLT-II Learning Curve in Multiple Sclerosis

Figure 7

The averaged learning curves over cluster referring to lower memory functioning and cluster referring to higher memory functioning for healthy female participants and MS female patients, using 𝐵 3 or 𝐵 4 . Empty circles—cluster referring to higher memory functioning using 𝐵 3 in healthy female participants; 𝐵 2 = 0.69; 𝐵 3 = 8.56; 𝐵 4 = 14.43. Empty diamonds—cluster referring to higher memory functioning using 𝐵 4 in healthy female participants; 𝐵 2 = 0.66; 𝐵 3 = 7.67; 𝐵 4 = 14.63. Filled circles—cluster referring to lower memory functioning using 𝐵 3 in MS female patients; 𝐵 2 = 0.63; 𝐵 3 = 5.06; 𝐵 4 = 11.62. Filled diamonds—cluster referring to lower memory functioning using 𝐵 4 in MS female patients; 𝐵 2 = 0.86; 𝐵 3 = 5.41; 𝐵 4 = 9.88. In healthy female participants 𝐵 3 is higher in cluster referring to higher memory functioning using 𝐵 3 ( 𝑃 = . 0 1 9 ) in comparison with cluster referring to higher memory functioning using 𝐵 4 . In MS patients 𝐵 4 ( 𝑃 = . 0 0 3 ) is higher in the cluster referring to lower memory functioning using 𝐵 3 versus cluster referring to lower memory functioning using 𝐵 4 . 𝐵 3 ( 𝑃 = . 0 0 0 0 5 ) and 𝐵 4 ( 𝑃 = . 0 0 0 8 ) differs highly significant between cluster referring to higher memory functioning for healthy females and cluster referring to lower memory functioning for MS females using 𝐵 3 . Besides 𝐵 3 ( 𝑃 = . 0 0 0 6 ) and 𝐵 4 ( 𝑃 = . 0 0 0 2 ) differs highly significant between cluster referring to higher memory functioning for healthy females and cluster referring to lower memory functioning for MS females using 𝐵 4 .
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