Brain Abnormalities in Neuromyelitis Optica Spectrum Disorder

Table 1

NMO spectrum [8].

NMO
Limited form of NMO
Idiopathic single or recurrent events of longitudinally extensive myelitis (≥3 vertebral segment spinal cord lesions seen on MRI)
Optic neuritis: recurrent or simultaneous bilateral
Asian optic-spinal multiple sclerosis
Optic neuritis or longitudinally extensive myelitis associated with systemic autoimmune disease
Optic neuritis or myelitis associated with brain lesions typical of NMO (hypothalamic, corpus callosal, periventricular, or brainstem)