Review Article

Brain Abnormalities in Neuromyelitis Optica Spectrum Disorder

Table 2

Revised criteria for the diagnosis of NMO [7].

Optic neuritis
Acute myelitis
At least two of the following three supportive criteria
 Contiguous spinal cord MRI lesion extending over at least
 three vertebral segments
 Onset brain MRI not meeting the diagnostic criteria for MS
 NMO-IgG seropositivity status