Review Article

Plasma Exchange in Severe Attacks of Neuromyelitis Optica

Table 1

Disability measured as EDSS during spinal attacks stratified with basal impairment. St: steroid-only-treated group; 𝑆 𝑡 + 𝑃 𝐸 : steroid- and PE-treated group. Values are given as mean (SD) (from [37]).

Basal EDSS (null)Basal EDSS (1.0 to 5.5)Basal EDSS (≥6.0)
St S t + P E 𝑃 St S t + P E 𝑃 St S t + P E 𝑃
( 𝑛 = 1 7 )( 𝑛 = 7 )( 𝑛 = 2 6 )( 𝑛 = 1 3 )( 𝑛 = 2 4 )( 𝑛 = 9 )

Basal EDSS0 (0)0 (0)0.993.9 (0.8)3.9 (1.6)0.597.4 (1.0)7.1 (0.8)0.52
Acute EDSS7.1 (1.5)7.6 (1.2)0.527.6 (1.3)7.6 (1.1)0.678.9 (0.9)8.6 (0.6)0.24
Residual EDSS5.9 (1.9)2.1 (1.9)<0.015.8 (1.6)5.1 (1.1)0.218.5 (1.1)7.6 (1.0)0.05
ΔEDSS5.9 (1.9)2.1 (1.9)<0.012.0 (1.5)1.2 (1.6)0.101.1 (0.8)0.5 (0.8)0.11