Research Article
Adding to the Burden: Gastrointestinal Symptoms and Syndromes in Multiple Sclerosis
Table 3
Impact of reported affective spectrum disorder on MSIS score, gastrointestinal symptoms, and gastrointestinal syndromes.
| | Affective spectrum disorder | No affective spectrum disorder | Significance |
| | 95 (men = 16) | 123 (men = 32) | Sex | MSIS—overall | | | P < 0.01 | Physical | | | | Psychological | | | P < 0.01 | Globus | 2 | 5 | | Chest pain | 5 | 5 | | Heartburn | 10 | 14 | | Dysphagia | 21 | 12 | P = 0.02 | Dyspepsia | 23 | 13 | P = 0.012 | Nausea | 11 | 5 | | Vomiting | 2 | 1 | N/D | Belching | 9 | 7 | | IBS | 26 | 16 | P = 0.013 | Constipation | 38 | 42 | P = 0.45 | Incontinence | 14 | 19 | P = 0.96 |
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