Quantitative MRI Demonstrates Abnormality of the Fornix and Cingulum in Multiple Sclerosis
Tractography of the cingulum. Regions of interest were drawn on coronal sections. The first region was drawn on a coronal slice through the body of the corpus callosum, where cingulum fibers have an anteroposterior orientation (a). The second (b) and third (c) regions were drawn surrounding the area directly rostral to the corpus callosum at its anterior and posterior tips. The left and right cingula reconstructions were completed individually. Streamlines that passed through all three regions of interest were included in the study analysis and were terminated at the anterior and posterior regions. Three-dimensional reconstruction of the left cingulum in an MS case (d).