Review Article

The Gap in the Current Research on the Link between Health Locus of Control and Multiple Sclerosis: Lessons and Insights from a Systematic Review

Table 1

Grid used for assessing the papers (adapted from Moher).

CategoryDescriptionGrading

ASample size calculation, estimating the minimum number of participants required to detect a significant difference among compared groups0 = did not exist/not mentioned/not clear
1 = was reported but not confirmed
2 = reported and confirmed

BRandomization and allocation concealment methods0 = clearly inadequate
1 = possibly adequate
2 = clearly adequate

CClear definition of inclusion and exclusion criteria0 = no
1 = yes

DCompleteness of follow-up (specified reasons for withdrawal and drop-outs for each group)0 = no/not mentioned/not clear
1 = yes/no withdrawals or drop-outs occurred

EExperimental and control groups comparable at study baseline for important prognostic factors0 = no
1 = unclear/possibly not comparable for one or more important prognostic factors
2 = clearly adequate

FPresence of masking0 = no
1 = unclear/not complete
2 = yes

GAppropriate statistical analysis0 = no
1 = unclear/possibly not the best method applied
2 = yes