The Frequency of Anti-Aquaporin-4 Ig G Antibody in Neuromyelitis Optica and Its Spectrum Disorders at a Single Tertiary Referral Center in Malaysia

Table 3

Showing relationship between seropositivity in NMO/NMOSD/High risk syndromes for NMOSD and clinical parameters.

Parameter (Mean)	Seropositive	Seronegative	value, <0.05 is significant
Age at onset	32.9 ± 11.8 years	30.3 ± 10.8 years	0.25
Duration of disease	2.6 ± 1.0 years	2.3 ± 0.8 years	0.23
Number of relapses	5.15 ± 4.4	2.10 ± 1.7	0.001
Annual relapse rates	1.17 ± 0.7	0.91 ± 0.8	0.015
EDSS	4.5 ± 2.4	2.4 ± 2.6	<0.001
Length of spinal cord lesion	6.66 ± 4.9	2.90 ± 2.5	<0.001
Number of cord lesions	1.17 ± 0.96	0.96 ± 0.93	0.025

Abbreviations: EDSS: Expanded disability status scale.