Leg Spasticity and Ambulation in Multiple Sclerosis

Table 2

Descriptive and effect size data for differences in ambulatory outcomes between the samples of persons who have multiple sclerosis with (𝑛=44) and without (𝑛=40) leg spasticity.

Variable	Group	Mean (SD)	Median	Range	SD pooled	Cohen’s 𝑑	Statistic	𝑃 value
6MW (ft)	No spasticity	1525 (379)	1623	664–2538	398	−0.86	−3.93	<0.0001
	Spasticity	1182 (417)	1188	294–2019
T25FW (sec)	No spasticity	5.8 (2.1)	5.0	3.1–12.6	2.9	0.72	3.11	<0.005
	Spasticity	7.9 (3.7)	7.6	3.7–24.5
TUG (sec)	No spasticity	7.2 (2.8)	6.9	3.3–15.2	4.4	0.84	3.61	<0.001
	Spasticity	10.9 (5.7)	9.6	4.4–33.5
MSWS-12	No spasticity	31.3 (26.9)	30.2	0–85.4	24.4	1.09	4.98	<0.0001
	Spasticity	58.0 (22.1)	62.5	14.6–93.8
O2 Cost (mL·kg^−1·m^−1)	No spasticity	0.197 (0.040)	0.186	0.143–0.317	0.063	0.75	3.20	<0.001
	Spasticity	0.244 (0.083)	0.224	0.137–0.556
Accelerometry (steps·d^−1)	No spasticity	4708 (2747)	4376	630–13136	2437	−0.45	−2.07	<0.05
	Spasticity	3601 (2155)	3089	419–8178

Note: SD: standard deviation; 6MW: 6-minute walk; T25FW: timed 25 foot walk; TUG: timed up-and-go; MSWS-12: Multiple Sclerosis Walking Scale-12; O₂ cost: oxygen cost of walking.