Review Article
Correlations between MRI and Information Processing Speed in MS: A Meta-Analysis
Table 1
Holm-Bonferroni Investigation into the relationships between whole-brain MRI measures and information processing tests.
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The most significant value in an analysis had to be lower than the threshold in order to reject any null hypotheses. Reported values are assumed equal to the maximum possible, for example, is tested as . Where multiple values are reported for the same relationship (possibly adjusted versus unadjusted), the most insignificant value was used. Number of studies with RRMS + Mixed only do not necessarily sum to total studies, as some studies had a 100% SPMS or benign MS population. “Number of tests” strongly corresponds to number of studies; rarely, studies had data on subgroups that could not be combined. MRI: magnetic resonance imaging; PASAT: paced auditory serial addition test; RRMS: relapse-remitting multiple sclerosis; SDMT: symbol digit modalities test; T2LV: T2-weighted lesion volume; NS: not significant. |