Adipsin Is Associated with Multiple Sclerosis: A Follow-Up Study of Adipokines

Table 2

Volumes of T1 and FLAIR lesions at baseline and follow-up (median (interquartile range)).

	T1 lesions (cm^3)			FLAIR lesions (cm^3)
	BL	1-YR	value	BL	1-YR	value
CIS	0.4 (0.0–0.6)	0.3 (0.2–0.8)	0.046	1.0 (0.3–2.2)	1.3 (0.5–3.1)	0.001
RRMS	1.4 (0.5–3.7)	3.0 (0.8–6.0)	0.001	6.3 (2.6–17.5)	14.0 (6.0–24.8)	0.00002
SPMS	5.8 (2.2–9.4)	6.5 (3.7–18.6)	0.041	18.4 (11.6–30.1)	29.3 (24.8–40.2)	0.004
PPMS	0.8 (0.6–2.8)	2.0 (0.9–4.7)	0.004	5.3 (3.1–10.4)	9.7 (6.8–15.1)	0.0004

RRMS: relapsing-remitting MS, SPMS: secondary progressive MS, PPMS: primary progressive MS, CIS: clinically isolated syndrome, and BL: baseline.
The intraindividual changes in the volumes of MRI over the follow-up period, Wilcoxon signed-rank test.
Compared to CIS group, Mann-Whitney test, .
^#Compared to SPMS, Mann-Whitney test, .