EDSS Change Relates to Physical HRQoL While Relapse Occurrence Relates to Overall HRQoL in Patients with Multiple Sclerosis Receiving Subcutaneous Interferon β-1a
Table 1
Baseline demographics and disease characteristics [6].
Baseline characteristic
Patients with data at Month 24 or ET visit ()
Patients without data at Month 24 or ET visit ()
Overall ()
Age, years, mean (SD)
39.0 (9.3)
37.1 (9.1)
38.7 (9.3)
Female, (%)
212 (76.5)
42 (73.7)
254 (76.0)
Caucasian, (%)
257 (92.8)
52 (91.2)
309 (92.5)
Employment status, (%)
Student
16 (5.8)
4 (7.0)
20 (6.0)
Full-time, part-time, or retired workers
194 (70.0)
33 (57.9)
227 (68.0)
Unemployed
66 (23.8)
20 (35.1)
86 (25.7)
Homemaker
1 (0.4)
0 (0.0)
1 (0.3)
Highest level of education achieved, (%)
Primary or secondary
119 (43.0)
25 (43.9)
144 (43.1)
Tertiary or above
158 (57.0)
32 (56.1)
190 (56.9)
MS classification, (%)
Relapsing-remitting
265 (95.7)
54 (94.7)
319 (95.5)
Secondary progressive
4 (1.4)
2 (3.5)
6 (1.8)
Clinically isolated syndrome
8 (2.9)
1 (1.8)
9 (2.7)
Time since onset of MS symptoms, months, median (range)
25.0 (0–422)
31.0 (4–251)
26.0 (0–422)
Time since MS diagnosis, months, median (range)
4.0 (0–386)
5.0 (0–203)
4.0 (0–386)
Previously received DMDs, (%)
53 (19.1)
15 (26.3)
68 (20.4)
EDSS score, (%)a
0
32 (11.6)
7 (12.3)
39 (11.7)
1.0–1.5
102 (36.8)
14 (24.6)
116 (34.7)
2.0–2.5
83 (30.0)
14 (24.6)
97 (29.0)
3.0–3.5
33 (11.9)
13 (22.8)
46 (13.8)
4.0–4.5
14 (5.1)
3 (5.3)
17 (5.1)
5.0–5.5
7 (2.5)
2 (3.5)
9 (2.7)
6.0–6.5
6 (2.2)
4 (7.0)
10 (3.0)
≥7.0
0
0
0
Mean (SD)
2.0 (1.3)
2.4 (1.6)
2.0 (1.4)
There were no significant differences in the baseline characteristics of patients with and without Month 24 or ET visits; baseline characteristics were compared using the 2-sided Mann-Whitney test (quantitative variables) or 2-sided Fisher’s exact test (qualitative variables). aPercentages add up to values slightly above 100% (100.1%) due to rounding up to one decimal place. DMD, disease-modifying drug; EDSS, Expanded Disability Status Scale; ET, early termination; MS, multiple sclerosis; SD, standard deviation.
