Review Article

Neuroimaging of Natalizumab Complications in Multiple Sclerosis: PML and Other Associated Entities

Figure 3

63-year-old woman with MS presenting with profound neurologic deterioration. (a) FLAIR image demonstrates characteristic PML lesions involving the subcortical U-fibers which also extent centrally to the periventricular surface. (b) T2-weighted image on the same patient demonstrates “granular” or “microcystic” foci (arrows).