The Effects of Aerobic Exercise on the Recovery of Walking Ability and Neuroplasticity in People with Multiple Sclerosis: A Systematic Review of Animal and Clinical Studies

Table 1

Methodological quality assessment of the clinical studies included in this review.

Articles included

PEDro scoring criteria

PEDro

(1)

(2)

(3)

(4)

(5)

(6)

(7)

(8)

(9)

(10)

(11)

Ahmadi et al. [37]

Y

Y

N

Y

N

N

N

N

N

Y

Y

4/10

Aydin et al. [38]

Y

Y

N

Y

N

N

N

Y

N

Y

Y

5/10

Dettmers et al. [39]

Y

Y

Y

Y

N

N

N

Y

N

Y

Y

6/10

Schulz et al. [40]

N

Y

N

Y

N

N

N

Y

N

Y

Y

5/10

Romberg et al. [41]

Y

Y

N

Y

N

N

N

Y

Y

Y

Y

6/10

Brændvik et al. [42]

Y

Y

N

Y

N

N

N

Y

Y

Y

Y

6/10

Collett et al. [43]

Y

Y

N

Y

N

N

Y

N

Y

Y

Y

6/10

Rampello et al. [44]

Y

Y

N

Y

N

N

Y

N

N

Y

Y

5/10

Briken et al. [45]

N

Y

N

Y

N

N

N

N

N

Y

Y

4/10

Vaney et al. [46]

Y

Y

Y

Y

N

N

N

N

Y

Y

Y

6/10

Schwartz et al. [47]

Y

Y

Y

Y

N

N

Y

Y

N

Y

Y

7/10

Straudi et al. [48]

N

Y

N

Y

N

N

Y

N

Y

Y

Y

6/10

Total score

9

12

3

12

0

0

4

6

5

12

12

(1) Eligibility criteria; (2) random allocation; (3) concealed allocation; (4) baseline comparability; (5) blind subjects; (6) blind therapists; (7) blind assessors; (8) adequate follow-up; (9) intention-to-treat analysis; (10) between-group comparisons; (11) point estimates and variability. eligibility criteria item in the PEDro scale does not contribute to the PEDro score. Y (yes) = 1; N (no) = 0. PEDro: Physiotherapy Evidence Database; : sum of scores; %: percentage.