Research Article

Telehealth-Delivered Cognitive Behavioral Therapy for Insomnia in Individuals with Multiple Sclerosis: A Pilot Study

Table 3

Primary and secondary outcomes at baseline (pre), reassessment (post), change score, and effect size. Data reported as mean (standard deviation). ISI: Insomnia Severity Index; PSQI: Pittsburgh Sleep Quality Index; MFIS: Modified Fatigue Impact Scale; FSS: Fatigue Severity Scale; SSES: Sleep Self-Efficacy Scale; SOL: sleep onset latency; SE: sleep efficiency; TST: total sleep time; PHQ-9: Patient Health Questionnaire, 9 items; GAD-7: Generalized Anxiety Disorder Assessment, 7 items; MSIS-29: Multiple Sclerosis Impact Scale, 29 items; ES: effect size.

Tele-CBTiF2F-CBTi
ChangeESChangeES

Primary outcomes
ISI-10.8 (3.8)<.0012.815-13.3 (4.9)<.0012.729.210
PSQI-7.1 (3.5)<.0012.006-6.7 (2.9)<.0012.314.785
MFIS-28.9 (13.1)<.0012.193-19.3 (18.2)<.0011.064.178
FSS-23.0 (16.1).0011.432-8.5 (16.2).0430.524.908
Secondary outcomes
SOL-35.1 (18.8)<.0011.959-33.3 (39.2).0251.117.893
SE13.5 (25.8).1120.53117.7 (8.8)<.0012.075.635
TST67.1 (103.1).0560.71573.0 (47.2).0011.572.870
SSES14.9 (7.2)<.0012.07711.2 (9.3)<.0011.221.317
PHQ-9-5.2 (4.6).0041.136-4.7 (5.9)<.0010.798.836
GAD-7-2.2 (5.3).2000.415-1.9 (3.4).0490.549.888
MSIS-29-23.4 (18.4).0021.265-10.7 (11.2).0150.955.870