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Journal of Neural Transplantation
Volume 1 (1989), Issue 3-4, Pages 95-103
http://dx.doi.org/10.1155/NP.1989.95

Tectal Tissue Grafted to the Midbrain of Newborn Rats: Effect of Donor Age on the Survival, Growth and Connectivity of Transplants

Department of Anatomy and Human Biology, The University of Western Australia, Nedlands, Perth, W.A. 6009, Australia

Copyright © 1989 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Tectal tissue from fetal (E15, E18, E20) and newborn (P0) rats was transplanted to the midbrain of newborn rats. Graft survival and size decreased with increasing donor age. Host retinal input was found in E15, E18 and E20 grafts; the specific pattern of retinal innervation was similar for all fetal donor ages.