Neural Plasticity

Neural Plasticity / 2005 / Article
Special Issue

Posture in the Picture: On the Relevance of Postural Control in Children with Developmental Motor Disorders

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Open Access

Volume 12 |Article ID 984010 |

Laurent Vinay, Faïza Ben-Mabrouk, Frédéric Brocard, François Clarac, Céline Jean-Xavier, Edouard Pearlstein, Jean-François Pflieger, "Perinatal Development of the Motor Systems Involved in Postural Control", Neural Plasticity, vol. 12, Article ID 984010, 9 pages, 2005.

Perinatal Development of the Motor Systems Involved in Postural Control


Motor behaviors of some species, such as the rat and the human baby, are quite immature at birth. Here we review recent data on some of the mechanisms underlying the postnatal maturation of posture in the rat, in particular the development of pathways descending from the brain stem and projecting onto the lumbar enlargement of the spinal cord. A short-lasting depletion in serotonin affects both posture and the excitability of motoneurons. Here we try to extrapolate to human development and suggest that the abnormalities in motor control observed in childhood—e.g, deficits in motor coordination—might have their roots in the prenatal period, in particular serotonin depletion due to exposure to several environmental and toxicological factors during pregnancy.

Copyright © 2005 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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