Figure 1: (a) Time spent in open arms of the elevated plus maze before and after exposure to stress. Following exposure to acute swim stress, rats spent less time in the open arms of the maze in comparison to the time spent in the open arms prior to the stress procedure (n = 8, P < .005), indicating increased anxiety. (b) Levels of corticosterone in control and stress rats. Acute swim stress induced elevation of serum corticosterone in the stressed rats (n = 6) compared to control rats (n = 8, P < .005).