Effect of Prenatal Protein Malnutrition on Long-Term Potentiation and BDNF Protein Expression in the Rat Entorhinal Cortex after Neocortical and Hippocampal Tetanization
Figure 1
(a) Scheme of two coronal planes of the rat brain
illustrating the positions of the stimulating electrodes in the occipital
cortex (OC) and ventral CA1 region of the left hemisphere, as well as the location
of the recording electrode in the ipsilateral entorhinal cortex EC. In the upper part are shown representative examples of the average of 30
successive responses evoked in the medial EC of one rat by ipsilateral
stimulation of the occipital cortex (A and B) or the ventral CA1 hippocampal region (C and D) at 0.2 Hz, obtained before (A and C) and after (B and D) tetanization. Calibration bars are
indicated. Upward potential deflection is negative. First and second arrows indicate, respectively, the beginning and the peak of the early negative (A) or early positive (C) wave, which served to calculate peak
amplitude or slope (amplitude/time
ratio on the nearest sample to the 10% and the 90% level) of the early component. (b) Onset and peak latencies
(values are means ± SEM, in millisecond) of the early component of EC
responses to test stimulus applied to either the OC or CA1 region before tetanization.
