Linking Cellular Mechanisms to Behavior: Entorhinal Persistent Spiking and Membrane Potential Oscillations May Underlie Path Integration, Grid Cell Firing, and Episodic Memory
Figure 1
(a) Example of persistent
firing in layer II pyramidal cell showing alternating cycles of spiking and nonspiking in data from Klink and Alonso [5]. (b) Simulation of grid
cell firing dependent upon cyclical persistent spiking gated by random movement
in a two-meter square environment. Spiking shown as black dots on trajectory in gray. (c) Simulation from same model
using rat trajectory from experimental data in an 85 cm square
environment.