Auditory Stimulation Dishabituates Olfactory Responses via Noradrenergic Cortical Modulation
Figure 2
(a) Representative raw recordings of
odor-evoked heart rate orienting responses (instantaneous beats/min) in
response to odor stimulation before and after habituation, and after
presentation of a 108 dB siren. (b) Schematic of experimental design.
Odor test pulses (3-4 repeats) were presented with at least 60-second
interstimulus intervals to determine mean baseline response magnitude. Then
repeated stimuli (20-second ISI) were presented to induce habituation which was
tested with 4 spaced stimuli similar to that during baseline (60-second ISI). To induce dishabituation, a 1–2-second siren
(upward arrows) was played 10–30 seconds prior to spaced odor stimuli.
