Research Article

Time-Dependent Expression of Arc and Zif268 after Acquisition of Fear Conditioning

Figure 5

Expression of Arc and zif268 protein in the dorsal hippocampus is induced by context exposure and associative learning, respectively. (a) Rats exposed to auditory fear conditioning (T) or contextual and auditory stimuli without shock (WN-CXT) show similar increases in Arc protein relative to unstimulated home cage (HC) controls. (b) Auditory fear conditioning produced increased zif268 protein expression in the dorsal hippocampus in comparison to HC animals. WN-CXT and SHK-only groups did not show significant changes from basal levels. Bar graphs represent the group means ± SEM. P*<.05 for ANOVA. P#<.05 for planned comparisons.
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(a)
139891.fig.005b
(b)