Dendritic Spines and Development: Towards a Unifying Model of Spinogenesis—A Present Day Review of Cajal's Histological Slides and Drawings
Figure 1
(a) Represents the first Cajal scientific drawing showing dendritic spines from a Purkinje cell of the hen, 1888. Inset shows dendritic spines digitally enlarged of the boxed region. (b) Purkinje cell and dendritic spines (inset) of the adult bird cerebellum taken from a Cajal’s histological preparation stained following the Golgi method. (c) drawing by Cajal [5] showing dendritic spines of pyramidal (A), Purkinje (B), basket (C) and Golgi cells (D). (d) dendritic spines and filopodia taken from Cajal histological preparations, and Golgi impregnation; 1, dendritic spines, pyramidal cell, parietal cortex, one-month-old human; 2, dendritic spines, Purkinje cell, adult cat cerebellum; 3, dendritic filopodia and spines, basket cell, cerebellum, of 17-day-old dog; 4, Golgi cell dendrite, cerebellum, of 17-day-old dog.
