Dendritic Spines and Development: Towards a Unifying Model of Spinogenesis—A Present Day Review of Cajal's Histological Slides and Drawings

Figure 11

(a) Illustrates a Purkinje cell, 17-day-old dog, Golgi method, Cajal histological preparation. (b) Three-dimensional reconstruction of a portion of the dendritic tree of this Purkinje cell. (c) Golgi-impregnated dendritic appendages of this Purkinje cell; 1: protospine; 2: thin dendritic spines; 3: small dendritic spines; 4: possible budding branchlets. (d) Boxed regions in (b); 1: protospine (green); 2: thin filopodia (green); 3: thin dendritic spines (arrow); 4: possible budding branchlet (arrow). (e) Purkinje cell, “cat almost adult” according to the label of the Cajal histological preparation, Golgi method. (f) Three-dimensional reconstruction of a portion of the dendritic tree of this Purkinje cell. (g) Golgi-impregnated dendritic appendages of this Purkinje cell; 1, dendritic filopodia; 2, thin dendritic spines; 3 and 4 sessile dendritic spines. (h):Boxed regions in (f); 1, dendritic filopodia; 2, thin dendritic spines; 3, 4, sessile dendritic spines and some thin dendritic spines.