Dendritic Spines and Development: Towards a Unifying Model of Spinogenesis—A Present Day Review of Cajal's Histological Slides and Drawings

Figure 13

(a) Extended focus images of pyramidal cells, bipolar phase, neocortex, dog fetus, Cajal histological preparation, Golgi method. (b) Boxed region in (a) showing some appendages (ap) on the soma and the initial portion of the apical trunk. (c) Pyramidal cells, cerebral cortex, layers I–III, newborn rabbit, Cajal histological preparation, Golgi method. (d) Filopodia, protospines and dendritic spines, pyramidal cells showed in (c) 1: filopodia giving rise to protospines; 2 and 3: protospines; 4: filopodia; 5 and 6: thin dendritic spines; 7 and 8: mushroom dendritic spines. (e) Pyramidal cell, phase of appearance of basilar dendrites and collateral oblique dendrites of the apical trunk, neocortex, layer III, human fetus, Cajal histological preparation, Golgi method.