Dendritic Spines and Development: Towards a Unifying Model of Spinogenesis—A Present Day Review of Cajal's Histological Slides and Drawings
Figure 4
Spinogenesis in the Purkinje cell branchlets contacting parallel fibers according to Larramendi [15, Figures 4 and 5] using electron microscopy, 14-day-old mouse. (a) Dendrites grow “long spine-like processes,” once the synaptic contact occurs with a parallel fiber, spines develop a terminal head and the parallel fiber forms a swelling. (b) Parallel fibers often form long synaptic adhesions with developing spines that subsequently decrease in size (synaptic adhesion waning).
