Review Article
Histaminergic Mechanisms for Modulation of Memory Systems
Table 5
Administration of drugs that act on the histaminergic system into the amygdala and memory performance.
| | Species | Amygdala site | Behavioral task | Histaminergic modulator | Effect on memory | Reference(s) |
| | Rat | Basolateral | Active avoidance | Histamine | ↓ | [144] | | Rat | Basolateral | Contextual fear conditioning | H3 receptor antagonists (ciproxifan, clobenpropit and thioperamide) | ↓ | [154] | | Rat | Basolateral | Contextual fear conditioning | H3 receptor agonists (RAMH or Immepip) | ↑ | [144, 155] | | Rat | Basolateral | Contextual fear conditioning | H3 receptor agonist (proxifan) | ↑ | [156] |
|
|
RAMH: (R)-(−)-alpha-methylhistamine.
|
