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Neural Plasticity
Volume 2011, Article ID 537659, 12 pages
Research Article

Diacylglycerol Signaling Underlies Astrocytic ATP Release

1Department of Neuroscience, Tufts University, 136 Harrison Avenue, Boston, MA 02111, USA
2Department of Neuroscience, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA 19104, USA

Received 7 January 2011; Accepted 5 May 2011

Academic Editor: Stuart C. Mangel

Copyright © 2011 Alison E. Mungenast. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure 1: Cultured astrocytes response to OAG stimulation with discrete calcium oscillations. Astrocytes loaded with the calcium indicator Fluo4 show little activity at baseline in a continuous perfusion of NHS. Upon the application of OAG (green box), discreet oscillations can be observed as uncoordinated increases in Fluo4 signal in different regions of the viewing field.

  1. Supplementary Material