Review Article

Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome

Figure 1

(a) Depiction of the distribution of miR-fmr1 in wild-type and FXS zebrafish neurons. (b) Sequence diagram of the miR-fmr1 precursor with both isoforms labeled. Polypyrimidine tract: PPT, nuclear import signal: NIS. (c) Map of wildtype zebrafish brain showing in situ hybridization expression patterns of miR-fmr1 ramRNAs from three sections: (1) cross-section of the lateral pallium, (2) longitudinal section of the pallium-neocortical junction, and (3) longitudinal section of the cerebellum [4].
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