Tumor Necrosis Factor Alpha Mediates GABAA Receptor Trafficking to the Plasma Membrane of Spinal Cord Neurons In Vivo
Figure 7
Graphical representation of combined findings from current research, Ferguson et al., 2008 [13], and Stellwagen et al., 2005 [10]. (a) Depiction of current findings that TNF causes a U-shaped response in total GABAAR in vivo. (b) Representation of findings from Ferguson et al. [13]that TNF causes an increase in total GluA1 in vivo. Green arrows represent the findings of Stellwagen et al., 2005 [10] that a particular dose of TNF elicits an increase in GluA1 and a decrease in GABAAR in vitro.
