Review Article

Widespread Structural and Functional Connectivity Changes in Amyotrophic Lateral Sclerosis: Insights from Advanced Neuroimaging Research

Figure 3

(a) Cortical thickness (CT) in patients with ALS versus controls in the preCG in mm ( ), corrected for age and whole brain CT. (b) Fractional anisotropy (FA) values along the CST and the corpus callosum, evaluated by DTI analysis, in patients with ALS and controls (** ; * ). (c) Number of functional connections in patients with ALS versus controls, corrected for age (threshold 0.40) ( ): this result was indicative of a relative sparing of functional connectivity in patients (derived from Verstraete et al. [21]).
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