Mouse Models of Down Syndrome as a Tool to Unravel the Causes of Mental Disabilities

Figure 1

Schematic representation of Hsa21 and syntenic regions of Mmu16, Mmu17, and Mmu10 and the different mouse models trisomic for different sets of genes orthologous to those of Hsa21. The flanking genes found at the boundaries of the triplicated region in each model are written in italics. Modified from [3, 137].