Effects of Antipsychotics on Dentate Gyrus Stem Cell Proliferation and Survival in Animal Models: A Critical Update

Table 1

Critical selection of most relevant papers published in the last 13 years.

Author	Year	Finding	Reason for selection
Bayer et al. [1]	1999	Genetic or environmental first hit affects brain development, a second hit later in life initiated the outbreak of schizophrenia	Comprehensive hypothesis concerning schizophrenia etiology
Arnold and Watt [21]	2001	Number of immature cells is increased in the olfactory epithelium of schizophrenics	First report on altered cell density in schizophrenics
Reif et al. [22]	2006	Cell proliferation is diminished in the dentate gyrus of schizophrenics	First report on altered cell proliferation in the human brain
Kippin et al. [23]; Wakade et al. [24]; Wang et al. [25]	2005; 2002; 2004	Typical and atypical neuroleptics enhance neurogenesis in the subventricular zone	Effects of neuroleptics on neurogenesis in the subventricular zone
Kodama et al. [26]; Wakade et al. [24]; Halim et al. [27]	2004; 2002; 2004	Atypical but not typical neuroleptics interfere with hippocampal neurogenesis	Effects of neuroleptics on neurogenesis in the hippocampus
Piontkewitz et al. [28]	2012	Risperidone partially restored impaired neurogenesis in poly I:C offspring	Effect of an atypical neuroleptic on neurogenesis in an model of maternal infection
Keilhoff et al. [29]	2010	Subchronic treatment with haloperidol ameliorated decreased neurogenesis and normalised behaviour in vitamin D-deficient rats	Effect of neuroleptics on neurogenesis in the vitamin D model
Keilhoff et al. [30]	2010	Risperidone and haloperidol promoted survival in stem cells in the hippocampus of rats subchronically treated with ketamine	Effects of typical and atypical neuroleptics on neurogenesis in the ketamine model