Functional Topography of Human Corpus Callosum: An fMRI Mapping Study
Callosal BOLD effect evoked by different tastants in normal subjects: (a) callosal foci evoked by the salty stimulus in 2 subjects (Al.M. and E.B.), both displaying activation in the anterior portion of the CC (green arrows), (b) callosal foci evoked by the neutral stimulus in subject E.B. displaying the activation in the anterior portion of the CC (green arrow), (c) callosal focus evoked by the sweet stimulus in 2 subjects (L.A. and E.B.), both exhibiting activation in the foremost portion of the corpus callosum (green arrows); a posterior focus, likely in the splenium, is also visible in subject L.A. (1), (d) callosal foci evoked by the bitter stimulus in subject L.E., displaying activation in the anterior portion of the CC (green arrow), and (e) callosal fibers arising from a cortical ROI selected in area GI (1, green circle) cross through the anterior CC (2 and 3, yellow arrows). Numbers on each brain represent the Talairach coordinates (, , ) of each focus (green arrows). On DTI images, a thin white line demarcates the CC. SS, Sylvian sulcus.