Figure 5: Moderate treadmill exercise increased glutamine synthetase activity in hippocampus of rats. Glutamate uptake and glutamine synthetase (GS) activity in the hippocampus of rats submitted to moderate treadmill exercise (20 min/day, 5 days/week during four weeks) were analyzed. Hippocampi were dissected out and chopped into 0.3 mm slices for measurement of glutamate uptake (a) or homogenized for measurement of GS activity (b). Values are mean ± standard error of control/sedentary (SED) ( ) and exercise (EXE) ( ) group. *means significant differences from control (Student’s -test, ).