Structural Brain Changes Following Left Temporal Low-Frequency rTMS in Patients with Subjective Tinnitus

Table 1

Demographical data and clinical characteristics for both independent subgroups.

	VBM data at baseline, day 12, and day 90; (𝑛=41)	VBM data at baseline and day 12; (𝑛=36)	Group comparison
				𝑃 value
Gender	32 m (78%); 9 f (22%)	27 m (75%); 9 f (25%)	𝜒^2 (1.77) = 0.10	0.752
Age (years)	50.72±13.37	50.79±13.28	𝑇(75) = −0.02	0.983
Tinnitus laterality	10% right; 15% left; 75% bilateral	14% right; 14% left; 72% bilateral	𝜒^2(2.77) = 0.32	0.853
Tinnitus duration (years)	8.97±8.36	7.57±6.74	𝑇(75) = 0.80	0.427
TQ (baseline)	36.61±17.78	39.56±18.21	𝑇(75) = −0.72	0.476
Loudness (baseline)	6.32±2.04	6.00±2.11	𝑇(75) = 0.67	0.441
Mean hearing threshold [dB HL]	21.67±11.49; (𝑁=29)	19.06±12.85; (𝑁=28)	𝑇(55) = 0.81	0.421
Hyperacusis	51% (𝑛=39)	68% (𝑛=22)	𝜒^2(2.61) = 2.31	0.316

TQ: Tinnitus Questionnaire.
Loudness: how STRONG or LOUD is tinnitus at present (0 not at all, 10 extremely strong or loud).
Mean hearing threshold: average of all thresholds measured bilaterally ranging from 125 Hz to 8 kHz).