Research Article

Effect of the Entorhinal Cortex on Ictal Discharges in Low-Mg2+-Induced Epileptic Hippocampal Slice Models

Table 2

Statistical analysis results of VPA effects on the propagation speed of epileptiform discharges in the two slice models (mean ± SEM, ).

Speed (mm/s)HP (interictal)EC-HP (interictal)EC-HP (ictal)
AnterogradeRetrogradeAnterogradeRetrograde

Control183.5 ± 64.9182.7 ± 58.7175.8 ± 50.9150.2 ± 43.7208.6 ± 22.2
VPA150.1 ± 48.3170.1 ± 37.6159.4 ± 54.9168.7 ± 54.6/
Wash158.3 ± 54.7174.9 ± 49.1172.4 ± 71.6168.9 ± 22.5196.0 ± 25.2

HP: hippocampal slice; EC-HP: combined EC-hippocampal slice.